Oops, she did it again!
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During her performance of "(You Drive Me) Crazy" (at the very end of the video), the 33-year-old pop princess toppled over in her sky-high heels and then sat there for a moment, clearly injured from the fall.
The embarrassing moment was caught on video by a few fans in the audience, and Spears even took to her Twitter to address the injury.
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"Thank you for all of the sweet wishes!" she wrote on Thursday. "Had a little scare on stage tonight with my ankle but I'm ok!"
Will the show go on? Spears is a resident at Planet Hollywood for her "Piece of Me" show, and her next show is scheduled for May 1. The "Pretty Girls" singer has a two year deal with the venue that reportedly earns her $15 million per year ($310,000 per show).