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SABMiller, one of the world's biggest brewers, says its chairman, Graham Mackay has died after suffering from a brain tumor.

The 64-year old Mackay helped lead the company through some of its most dramatic recent moments as it moved from its South African roots to become a massive global player with operations in 75 countries.

He became chief executive of South African Breweries Plc upon its listing on the London Stock Exchange in 1999.

He led SABMiller's global expansion, including the acquisition of Miller Brewing Company in the United States and the subsequent re-naming of it as SABMiller plc. He also was instrumental in the joint venture between SABMiller and Molson Coors in 2008; and the acquisition of Foster's in Australia, 2011.

John Manser was named chairman Wednesday.