“It is not coincidental that at times there is a resurgence of symbols typical of Nazism,” he said. “And I must confess to you that when I hear a speech (by) someone responsible for order or for a government, I think of speeches by Hitler in 1934, 1936."
He said persecution against Jews, Gypsies and "people with homosexual tendencies" represented a "culture of waste."
“These are actions that are typical of Nazism, that with its persecution of Jews, Gypsies, people with homosexual orientation, represent an excellent model of the throwaway culture and culture of hatred," Francis said.
He did not single out any particular politician or government.
Several countries have laws declaring homosexuality illegal; leaders such as President Jair Bolsonaro of Brazil have a history of making homophobic and racists comments.
Francis also denounced race-based police brutality and corporate crimes against the environment, which he called a sin.
The Associated Press contributed to this report.