Get all the latest news on coronavirus and more delivered daily to your inbox. Sign up here.
The death toll in Italy over the past 24 hours rose by 427 to 3,405, officials said.
Some 3,245 people have died in China since the virus first emerged there late last year, but Italy's outbreak only came to light on Feb. 21.
The developments come after the World Health Organization last week named Europe the new epicenter of the coronavirus pandemic. Since March 9, Italy has been under a nationwide lockdown meant to help curb the spread of the virus by effectively shutting down most aspects of public life.
Italy entered its second week of the lockdown by implementing new measures Tuesday that require Italians to fill out a police-issued self-declaration form before going outside.
Residents must state who they are, where they intend to go and for what reason. The form also requires residents to disclose that they have not tested positive for COVID-19 and are not currently taking part in a 14-day quarantine.
Overall, Italy has recorded 41,035 infections, more than half of the world’s positive cases, according to the Associated Press. The tally nearly doubled in the past five days while deaths in the country more than doubled.
Italy’s health care system has been overwhelmed by the virus, and on Thursday a visiting Chinese Red Cross team even criticized the failure of Italians to fully quarantine and take the national lockdown seriously.
Italy reached the bleak milestone the same day that Wuhan, the Chinese city where the coronavirus first emerged three months ago, recorded no new infections.
Health authorities have cited a variety of reasons for Italy’s high toll, key among them its large population of elderly people, who are particularly susceptible to serious complications from the virus, though severe cases have also been seen in younger patients. Italy has the world’s second-oldest population, and the vast majority of its dead — 87 percent — were over 70.
Spain has been the hardest-hit European country after Italy, and in Madrid on Thursday a four-star hotel began operating as a makeshift hospital for coronavirus patients.
Fox News' Danielle Wallace, Chris Irvine, and the Associated Press contributed to this report.