Watch "The Big Story Weekend" Saturday and Sunday at 9 p.m ET

Saturday, August 27

A new development in the Natalee Holloway (search) case! Brothers Satish and Deepak Kalpoe, who were previously detained in the disappearance of Natalee, have been re-arrested on suspicion of premeditated rape and murder. A third person, said to be a friend of the currently detained Joran van der Sloot, was also detained. What new evidence led to these most recent arrests? We'll get the latest from Aruban attorney Arlene Ellis-Schipper, El Diario reporter Giovanni Lane and Julia Renfro, editor-in-chief of Aruba Today.

Then, we'll get Natalee's family's reaction on this latest development from Natalee's father and stepmother, Dave and Robin Holloway and Natalee's stepfather, Jug Twitty.

And, twenty-year-old Julie Popovich (search) has been missing for over two weeks after a night out with her friends in Columbus, Ohio. Is foul play involved?

Plus, Hurricane Katrina (search) is churning in the Gulf of Mexico and on a path to make landfall anywhere from the Florida Panhandle to Louisiana as early as Monday, possibly as a Category 4 storm. We'll have the latest on the killer 'cane.

Sunday, August 28

We'll be joined by:

Dave and Robin Holloway, Natalee's father and stepmother
Jug Twitty, Natalee's stepfather
Tito Lacle, investigative reporter for Aruba Today
Art Wood, former Secret Service agent
Chris Lejeuz, Aruban attorney
Mike Powers, private investigator
Dr. Michael Baden, forensic pathologist
Gil Alba, former NYPD detective

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