Mathers, who is seeking financial support, attorney fees and joint custody of the couple's 10-year-old daughter, Hailie Jade Scott, was seen being escorted out of the building by a sheriff's deputy.
Her lawyer, Michael J. Smith, declined to comment. A message seeking comment was left Thursday with Eminem's attorney, Harvey Hauer.
Eminem, whose real name is Marshall Bruce Mathers III, was not seen by reporters at the courthouse, but he was present for the hour-long meeting before Court Referee David Elias, court officer Mark Mileski said.
The 33-year-old Grammy-winning rapper filed for divorce April 5.
Eminem and Mathers were remarried in Rochester on Jan. 14, a month after the couple announced they were getting back together. Their first marriage was from 1999 to 2001.
Macomb County Circuit Judge Antonio Viviano, who was originally scheduled to preside over Thursday's hearing, had set a deadline of Aug. 25 for completion of depositions, interrogatories, pension evaluations and other matters.
A settlement conference is scheduled for Sept. 19.
Eminem has won nine Grammys, including best rap album for "The Slim Shady LP," "The Marshall Mathers LP" and "The Eminem Show." He won an Oscar for the song "Lose Yourself" from "8 Mile," the semi-autobiographical 2002 film in which he starred.