Philadelphia, PA – Tom Brady threw for 361 yards and three 20.
Philadelphia got off to a flying start by taking a quick 10-0 advantage, but the Patriots outscored the Eagles 38-10 the rest of the way.
Wes Welker caught eight balls for 115 yards and two touchdowns, while Deion Branch added 125 yards receiving on six catches.
BenJarvus Green-Ellis added a pair of rushing scores for New England (8-3), which has outscored its opponents 109-39 during its three-game winning streak.
Vince Young got the start for the Eagles as Michael Vick missed his second consecutive game with a pair of broken ribs. Young completed 26-of-48 passes for 400 yards with a touchdown and an interception.
LeSean McCoy totaled 31 yards on just 10 carries for the Eagles (4-7), who fell to 1-5 at Lincoln Financial Field this season.
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