Chiney Ogwumike had 18 points and 12 rebounds, Kayla Pedersen had 11 points and 14 rebounds and No. 4 Stanford handed Oregon its most lopsided loss of the season in a 91-56 victory Thursday.

Nnemkadi Ogwumike and Sarah Boothe were each just two rebounds away from giving the Cardinal (17-2, 8-0 Pac-10) four players with double doubles as both had 16 points and eight rebounds. Jeanette Pohlen also scored 17.

Stanford handled Oregon inside. It outrebounded the Ducks 68-32, scored 52 points in the paint and had 24 points off 25 offensive rebounds.

The win was the 11th straight for Stanford since losing in overtime to Tennessee on Dec. 19.

It was also its 12th straight win against the Ducks (12-7, 3-5), who got 21 points from Nia Jackson and 15 points from Amanda Johnson.

Oregon made just 3 of 32 3-pointers and shot 25 percent overall from the field.

The last time these teams met on Feb. 18, 2010, the Cardinal won by the largest margin in the history of the rivalry 104-60. On Thursday, they came close to setting a new standard.

Stanford jumped out to a 19-1 lead in the first half and led 41-25 at halftime. The Ducks missed their first 15 shots before Johnson scored on a putback with 10:21 to play in the half.

The Cardinal pounded the ball inside to the Ogwumike sisters to start the second half and the two forwards combined to score Stanford's first 16 points of the half as the Cardinal extended their lead to 57-27 with 14:57 to play. From there the rout was on and Stanford pulled its starters with 7:01 to play.

Chiney Ogwumike, a 6-foot-3 freshman, finished 8 for 18 from the field and also had three of Stanford's season-high 10 blocks. Nnemkadi Ogwumike, a 6-2 junior, was 4 for 10 from the field but made 8 of 13 free throws.

Cardinal freshman guard Toni Kokenis, a key reserve, was ruled unavailable for the game following shootaround earlier Thursday.

Kokenis also didn't dress Saturday against Southern California after getting fouled in the head in the closing minutes of last Thursday's win over UCLA. She experienced slight headaches Friday and didn't practice, then was evaluated Saturday. The school said she didn't sustain a concussion but was being held out as a precaution. Kokenis had been expected back for games at Oregon and Oregon State this week.