(SportsNetwork.com) - Kyle Lohse hopes for redemption and will try to get the Milwaukee Brewers back on the winning track when they meet the Pittsburgh Pirates in the middle installment of a three-game set at PNC Park.

Lohse suffered a 10-2 defeat to the Pirates on Sunday at Miller Park. The 36- year-old right-hander was touched for eight hits and four runs over 6 1/3 innings. He is 11-4 with a 3.81 ERA in 24 career games (23 starts) against the Pirates. Lohse has gone 6-2 with a 4.35 ERA in 15 career games (14 starts) at PNC Park.

Jeff Locke counters on the mound for the Pirates. The lefty made his season debut in last Friday's 6-2 win over the Brewers and held them to two runs in six innings. He has made eight career starts against Milwaukee and has fashioned a 3-2 record to go along with a 3.86 ERA.

On Friday, Starling Marte hit a two-run home run and scored twice as the Pirates grabbed a 6-3 win. Josh Harrison, Andrew McCutchen, Pedro Alvarez and Sean Rodriguez each drove in a run for the Pirates, who snapped a two-game slide.

Vance Worley (1-1) went six innings and allowed two runs on six hits while walking four and striking out six.

"They were aggressive up there and I made sure I kept them more off-balance," Worley said.

Gerardo Parra drove in two runs, Jean Segura brought in the other while Khris Davis was 3-for-4 with a run scored for the Brewers, who have lost their last three. Jimmy Nelson (1-1) allowed three runs on five hits in five innings on the mound.

"I wasn't quite as sharp, but you're not going to be sharp every time out," Nelson said.

Milwaukee was 12-7 versus the Pirates last season, despite being outscored by the Bucs, 81-66.