Updated

Detroit, MI (SportsNetwork.com) - Detroit Lions running back Reggie Bush and left tackle Riley Reiff are inactive for Thursday's Thanksgiving Day game against the Chicago Bears.

It is the third straight game that Bush has missed due to an ankle injury as the USC product was limited in practice during the week.

Reiff had suffered a left knee injury in last week's loss at New England and was a limited participant in Wednesday's walkthrough after missing practice on Monday and Tuesday.

Rookie Cornelius Lucas will make his first start at left tackle.

Guard Larry Warford and defensive tackle Nick Fairley are both out with knee injuries for the Lions.