This week's men's basketball showdown between No. 21 Kentucky and archrival Louisville in Lexington has been postponed because of multiple positive COVID-19 tests within the Cardinals' program.

Louisville interim athletic director Josh Heird stated in a release that team-related activities have been paused indefinitely.

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The Bluegrass rivalry matchup that was scheduled for Wednesday between the school located 80 miles apart has been played annually since the 1982-83 season. A release from Kentucky on Monday morning stated that the athletics department is seeking a replacement game for the Wildcats (8-2) for either Wednesday or Thursday at Rupp Arena.

Southeastern Louisiana Lions forward Jalyn Hinton (0) drives past Louisville Cardinals forward Samuell Williamson (10) during a mens college basketball game between the SE Louisiana Lions and Louisville Cardinals on December 14, 2021 at the KFC Yum! Center, in Louisville, KY.  (Photo by Jeffrey Brown/Icon Sportswire via Getty Images)

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Kentucky is coming off Saturday's 98-69 rout of North Carolina in the CBS Sports Classic in Las Vegas, a matchup rescheduled after both schools' opponents pulled out following COVID issues. Louisville lost 82-72 on Saturday at in-state rival Western Kentucky without senior center Malik Williams, who was reportedly out because of COVID protocols.