Philadelphia Eagles defensive end Josh Sweat will not play in Sunday’s NFC wild-card playoff game against the Tampa Bay Buccaneers.

Sweat was listed on the injury report with an illness and came into the game listed as questionable. He did not practice the entire week, and the Eagles deactivated him before the game.

CLICK HERE FOR MORE SPORTS COVERAGE ON FOXNEWS.COM

Josh Sweat of the Philadelphia Eagles

Josh Sweat of the Philadelphia Eagles looks on prior to a game against the Dallas Cowboys at Lincoln Financial Field Jan. 8, 2022, in Philadelphia. (Mitchell Leff/Getty Images)

Before the game Sunday, the NFL Network reported there was something much more serious going on with Sweat than previously thought. 

Sweat reportedly underwent an emergency medical procedure to address a "life-threatening situation" Tuesday, and the Eagles and their medical team "did everything possible" to try and get Sweat ready to play the Buccaneers, according to the report. It was determined Sweat would sit out. 

TOM BRADY HAS ONE BUCS COACH FEARING THIS SEASON COULD BE IT

Josh Sweat of the Philadelphia Eagles

Josh Sweat of the Philadelphia Eagles looks on from the sideline during a game against the New York Jets at MetLife Stadium Dec. 5, 2021, in East Rutherford, N.J. (Steven Ryan/Getty Images)

Philadelphia coach Nick Sirianni said earlier in the week that Sweat had been suffering some abdominal pain. The Philadelphia Inquirer reported the issue was not a ruptured appendix.

Sweat’s become a key member of the Eagles’ defense over the last two seasons, signing a 3-year, $40 million contract extension earlier this season. In 2021, he played in 16 games and started 13 of them, recording 7.5 sacks along with 45 total tackles. Sweat’s absence will be a big loss for the Eagles as the team gets set to face Tom Brady and the Buccaneers.

Josh Sweat of the Philadelphia Eagles

Josh Sweat of the Philadelphia Eagles reacts while exiting the field after a loss to the Las Vegas Raiders at Allegiant Stadium Oct. 24, 2021, in Las Vegas.  (Sam Morris/Getty Images)

CLICK HERE TO GET THE FOX NEWS APP

Philadelphia’s defense was ranked 18th in points allowed and 10th in yards allowed this season. Sweat had six tackles and a QB hit in the team’s 28-22 loss to Tampa Bay earlier this season.