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At an April 2008 fund-raiser in San Francisco, Barack Obama let loose with his famous "they cling to their guns or religion" line. Last Saturday at a West Newton, Mass., fund-raiser, the president said, "facts and science and argument [do] not seem to be winning . . . because we're hard-wired not to always think clearly when we're scared."

Memo to White House: Calling voters stupid is not a winning strategy.

The economy and jobs are the No. 1 issue in every poll. Yet Mr. Obama of late has talked about immigration reform and weighed in (unprompted) on the Ground Zero mosque. He devoted Labor Day to an ineffective Mideast peace initiative. He demeans large blocs of voters and now is ending his midterm pitch with attacks on nonexistent foreign campaign contributions and weird assertions that "the Empire is striking back."

Meanwhile, Republicans have talked about little else than the economy—drawing attention to lackluster job growth, the failed stimulus, out-of-control spending, escalating deficits and the dangers of Obamacare.

Karl Rove is the former senior adviser and deputy chief of staff to President George W. Bush. He is a Fox News contributor and author of "Courage and Consequence" (Threshold Editions, 2010).

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