Seminole Statement: Winston, No. 5 Florida State crush No. 3 Clemson 51-14

Florida State quarterback Jameis Winston (5) celebrates his touchdown run against Clemson during the second half of an NCAA college football game, Saturday, Oct. 19, 2013, in Clemson, S.C. Offensive linesman Bobby Hart is at left. (AP Photo/Mike Stewart) (The Associated Press)

Clemson linebacker Spencer Shuey (33) hits Florida State quarterback Jameis Winston (5) during the second half of an NCAA college football game, Saturday, Oct. 19, 2013, in Clemson, S.C. (AP Photo/Mike Stewart) (The Associated Press)

Jameis Winston threw for 444 yards and three touchdowns and No. 5 Florida State crushed No. 3 Clemson 51-14 Saturday night, making statement that should be heard from Alabama to Oregon.

The Atlantic Coast Conference's game of the year, billed as maybe the league's biggest game ever, quickly became a Seminoles' seminar on how to take apart a top-five opponent on its hostile home turf.

Winston was 22 for 34 for Florida State (6-0, 4-0 ACC). His first throw was a 22-yard touchdown to Kelvin Benjamin, and he scrambled for a 4-yard touchdown that made it 41-7 with 4:04 left in the third quarter.

Tajh Boyd threw two interceptions for Clemson, and his first-quarter fumble was returned 37 yards for a touchdown by Mario Edwards. Clemson (6-1, 4-1) turned it over a season-high four times, including on the first play from scrimmage.