Indiana, Connecticut, Boston College and Washington will headline in the 19th annual 2K Sports Classic.
A total of 12 teams from across the country will compete in the event, with Indiana, Connecticut, Boston College and Washington hosting regional games in early November.
The four regional hosts will advance to the championship round, which will be played at Madison Square Garden from Nov. 21-22, while the remainder of the field will compete in subregionals held at campus sites.
Matchups for the championship round will be announced at a later date.
Alabama beat Villanova, 77-55, in the 2012 title game.