The 36-year-old, twice a winner of the NHL's Lady Byng Memorial Trophy for sportsmanship, formally called it quits more than a year after he played his last game and sat out the entire 2010-11 season for the St. Louis Blues.
"Today, I announce my retirement from professional hockey," Kariya said in a statement released by his agent.
"I would like to thank all of those who have been part of so many great memories - my teammates, coaches, team management and staff."
While Kariya spent his last three seasons playing for the St. Louis Blues, the seven-time All-Star is best known for the nine seasons he spent in California.
His best offensive season with the Mighty Ducks, now known as the Anaheim Ducks, came in 1995-96 when he had a career-high 50 goals to go along with 58 assists.
In 2003 Kariya led Anaheim to the Stanley Cup Finals, where they lost in a decisive seventh game to the New Jersey Devils. He was knocked unconscious during the series after a hit from Devils defenseman Scott Stevens.
(Reporting by Frank Pingue; Editing by Julian Linden)