EXCLUSIVE - Casey DeSantis, the wife of Gov. Ron DeSantis of Florida, has been diagnosed with breast cancer.

"I am saddened to report that Florida’s esteemed First Lady and my beloved wife has been diagnosed with breast cancer," the Republican governor said in a statement shared first with Fox News on Monday.

"As the mother of three young children, Casey is the centerpiece of our family and has made an impact on the lives of countless Floridians through her initiatives as First Lady. As she faces the most difficult test of her life, she will have not only have my unwavering support but the support of our entire family, as well as the prayers and well wishes from Floridians across our state. Casey is a true fighter, and she will never, never, never give up," the governor emphasized.

DeSantis family

Florida Gov. Ron DeSantis, first lady Casey DeSantis and their three children (left to right) Mamie, Madison, and Mason

Casey DeSantis, 41, is a former producer and Emmy award-winning television show host for the PGA tour. She was also a three-time equestrian national champion, as well as a runner-up NCAA division one champion.

Married since 2010, Casey and Ron DeSantis are the parents of Madison, 4, Mason, 3, and Mamie, 18 months, who was the first baby born in the Florida governor's mansion in more than half a century.

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During her tenure so far as Florida's first lady, DeSantis has spearheaded several major initiatives, including "Hope Florida — A Pathway to Prosperity, Economic Self-Sufficiency and Hope."