JACKSONVILLE, Fla. (AP) -- Jacksonville Jaguars receiver Marqise Lee is doubtful to play in the season opener against the Carolina Panthers.

Coach Gus Bradley all but ruled Lee out Friday, saying it's "unlikely that he will be ready to go."

Lee ran full speed on the sideline during practice Friday, but hasn't worked in team drills since injuring his right hamstring Aug. 5. The second-year pro caught 37 passes for 422 yards and a touchdown last season.

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Running back Toby Gerhart was listed as questionable with a strained abdominal muscle. Gerhart was limited in practice all week.

Linebacker LaRoy Reynolds (knee) practiced for the first time this week and was listed as probable.

Three starters already were ruled out: defensive end Andre Branch (knee), defensive tackle Sen'Derrick Marks (knee) and tight end Julius Thomas (hand).