Updated

Oil and gas production may explain a sharp increase in small earthquakes in the nation's midsection, a new study from the U.S. Geological Survey suggests.

The rate has jumped six-fold from the late 20th century through last year, the team reports, and the changes are "almost certainly man-made."

Outside experts were split in their opinions about the report, which is not yet published but is due to be presented at a meeting later this month.

The study said a relatively mild increase starting in 2001 comes from increased quake activity in a methane production area along the state line between Colorado and New Mexico. The increase began about the time that methane production began there, so there's a "clear possibility" of a link, says lead author William Ellsworth of the USGS.

The increase over the nation's midsection has gotten steeper since 2009, due to more quakes in a variety of oil and gas production areas, including some in Arkansas and Oklahoma, the researchers say.

It's not clear how the earthquake rates might be related to oil and gas production, the study authors said. They note that others have linked earthquakes to injecting huge amounts of leftover wastewater deep into the earth.

There has been concern about potential earthquakes from a smaller-scale injection of fluids during a process known as hydraulic fracturing, or fracking, which is used to recover gas. But Ellsworth said Friday he is confident that fracking is not responsible for the earthquake trends his study found, based on prior studies.

The study covers a swath of the United States that lies roughly west of Ohio and east of Utah. It counted earthquakes of magnitude 3 and above.

Magnitude 3 quakes are mild, and may be felt by only a few people in the upper floors of buildings, or may cause parked cars to rock slightly. The biggest counted in the study was a magnitude-5.6 quake that hit Oklahoma last Nov. 5, damaging dozens of homes. Experts said it was too strong to be linked to oil and gas production.

The researchers reported that from 1970 to 2000, the region they studied averaged about 21 quakes a year. That rose to about 29 a year for 2001 through 2008, they wrote, and the three following years produced totals of 50, 87 and 134, respectively.

The study results make sense and are likely due to man-made stress in the ground, said Rowena Lohman, a Cornell University geophysicist.

"The key thing to remember is magnitude 3s are really small," Lohman said. "We've seen this sort of behavior in the western United States for a long time."

Usually, it's with geothermal energy, dams or prospecting. With magnitude 4 quakes, a person standing on top of them would at most feel like a sharp jolt, but mostly don't last long enough to be a problem for buildings, she said.

The idea is to understand how the man-made activity triggers quakes, she said. One possibility is that the injected fluids change the friction and stickiness of minerals on fault lines. Another concept is that they change the below-surface pressure because the fluid is trapped and builds, and then "sets off something that's about ready to go anyway," Lohman said.

But another expert was not convinced of a link to oil and gas operations.

Austin Holland, the Oklahoma state seismologist, said the new work presents an "interesting hypothesis" but that the increase in earthquake rates could simply be the result of natural processes.

Holland said clusters of quakes can occur naturally, and that scientists do not yet fully understand the natural cycles of seismic activity in the central United States. Comprehensive earthquake records for the region go back only a few decades, he said, while natural cycles stretch for tens of thousands of years. So too little is known to rule out natural processes for causing the increase, he said.