Buddy Lazier will return to the Indianapolis 500 this season in a car fielded by Lazier Partners Racing.
The announcement Thursday was expected after the family-organized team also entered Lazier last season, one month after forming the team.
Lazier started 32nd last May, ran only 44 laps because of a fuel pressure issues, and retired with a 31st-place finish.
The 46-year-old Lazier will drive the No. 91 Chevrolet with sponsorship from the University of Iowa Stephen A. Wynn Institute for Vision Research. The research center specializes in cures for rare, inherited retinal diseases.
Jacqueline Lazier, the drivers' 12-year-old daughter, was born with Aniridia, which is a complete or partial absence of the colored part of the iris. Jacqueline has lost vision in her right eye.