Oliver Sacks, the eminent neurologist and acclaimed best-selling author, died Sunday at his home in New York City. He was 82.

The cause was cancer, The New York Times reported, citing the doctor’s longtime personal assistant.

Sacks revealed he had terminal cancer in February in an Op-Ed piece he wrote for the paper. He told readers his luck had run out, a rare tumor of the eye, an ocular melanoma, had spread to his liver.

His remarkable career included a number of hugely popular books, including “Awakenings” which became an Academy Award-nominated movie starring Robin Williams and Robert De Niro and “The Man Who Mistook His Wife for a Hat,” an exploration of unusual afflictions of the brain.

"When people die, they cannot be replaced," Sacks wrote in his Times essay. “They leave holes that cannot be filled, for it is the fate — the genetic and neural fate — of every human being to be a unique individual, to find his own path, to live his own life, to die his own death.”