Apple CEO Tim Cook condemned Sunday’s Orlando nightclub shooting as “senseless” and “unconscionable” during his keynote at Apple’s Worldwide Developers Conference (WWDC) in San Francisco Monday.

“It was a senseless, unconscionable act of terrorism,” said Cook, during his opening remarks at the Bill Graham Civic Auditorium. The Apple chief offered the company’s deepest sympathy to anyone affected by the horrific mass shooting.

“The Apple community is made up of people from around the world, from all different backgrounds and points of view,” said Cook, before asking the audience to rise for a moment of silence for the victims and their loved ones.

Related: Software and services on deck at Apple's WWDC event

Terrorist Omar Mateen killed at least 49 people in Orlando gay nightclub Pulse early Sunday before he was killed by law enforcement.

The Orlando shooting continues to trend heavily on social media with #OrlandoUnited one of the top trending U.S. topics on Twitter.

Facebook activated its Safety Check service for the first time in the U.S. after Sunday morning’s deadly shooting.

Related: Facebook activates Safety Check service after Orlando nightclub shooting

ISIS claimed responsibility for the attack Sunday afternoon via its Amaq news agency, according to Reuters.

Designed for times of disaster or crisis, Safety Check lets users in a specific area notify friends and family that they are safe. Users can also check on others in the affected area and mark friends as safe.

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