NFL

Colts' Holmes out for Monday night with neck injury

Jan 11, 2015; Denver, CO, USA; Indianapolis Colts center Khaled Holmes (62) in the 2014 AFC Divisional playoff football game against the Denver Broncos at Sports Authority Field at Mile High. Mandatory Credit: Chris Humphreys-USA TODAY Sports

Jan 11, 2015; Denver, CO, USA; Indianapolis Colts center Khaled Holmes (62) in the 2014 AFC Divisional playoff football game against the Denver Broncos at Sports Authority Field at Mile High. Mandatory Credit: Chris Humphreys-USA TODAY Sports

Khaled Holmes was hurt in the Colts' Week 7 loss.

Chris Humphreys USA TODAY Sports

Colts center Khaled Holmes has been ruled out for Monday night's showdown with the undefeated Panthers.

Holmes didn't return in the second half of last Sunday's game against the Saints after sustaining a minor neck injury in the second quarter.

More from FoxSports

Holmes didn't practice all week. Jonotthan Harrison entered the game for Holmes during the second half last Sunday. Harrison took reps at center with the first team all week at practice and likely will be the starter Monday night.

"This is the NFL. The next person has to be ready. Coach always says prepare as a starter, you never know when your number will be called," Harrison said. "Come game day, if my number is called, I know I'm prepared."