Receiver Josh Doctson caught two first-half touchdown receptions and TCU's defense smothered Minnesota's run-oriented attack for a 30-7 win Saturday.
TCU (2-0) forced five turnovers and held Minnesota (2-1) to 99 yards rushing — 134 below its average.
Doctson had a leaping grab with his right hand for a 7-yard score that increased TCU's lead to 17-0 early in the second quarter.
Mitch Leidner, Minnesota's starting quarterback, left the game early in the fourth quarter following a hard tackle. Leidner passed for 151 yards and three interceptions and also lost a fumble.
TCU held David Cobb to 41 yards on 15 carries. Cobb averaged 145.5 yards rushing in Minnesota's previous two victories.
The Gophers' lone score came on a 12-yard pass from freshman Chris Streveler to Maxx Williams with 10:56 to play.