Ann Coulter was encouraged to commit suicide during Saturday’s taping of “The Comedy Central Roast of Rob Lowe.”

“Ann is one of the most repugnant, hateful, hatchet-face b----es alive,” British comedian Jimmy Carr declared, as audience members cheered. “It’s not too late to change, Ann. You could kill yourself!”

The conservative commentator — eager to promote her new book, “In Trump We Trust” — was one of nine celebrities invited to take pot shots at the star of “The West Wing” and “St. Elmo’s Fire.”

But it was Coulter, 54, who spent much of the evening in the hot seat — at one point being labeled a “two faced b----h” and a “transvestite whore.”

Even Super Bowl hero Peyton Manning got in a few jabs, announcing, “As you all know, earlier this year, Ann Coulter won the Kentucky Derby!”

The event, hosted by Roastmaster David Spade, was taped at Sony Pictures Studios in Culver City, Calif. and featured NSFW routines by Manning, singer Jewel, “Karate Kid” actor Ralph Macchio, comic Nikki Glaser and Comedy Central star Jeffrey Ross.

Most joked about Lowe’s failed TV projects and the infamous sex tape he made with a 16-year-old girl in 1988.

But many of the evening’s best zingers were aimed directly at Coulter.

David Spade: “Ann hopes the Republicans can hold onto the House so she can still haunt it.”

Peter Davidson: “If you are here, Ann, who is scaring the crows away from our crops?”

Jewel: “As a feminist I can’t support everything that’s been said tonight. But as someone who hates Ann Coulter, I’m delighted.”

Ralph Macchio: “I respect you. You are the one female commentator who is not afraid to stand up ... to take a leak.”

Nikki Glaser: “Ann, you are awful. The only person you will ever make happy is the Mexican who digs your grave.”

Coulter sat expressionless through much of the evening and drew audible boos during her seven-minute set when she mentioned Republican presidential nominee Donald Trump.

“I am so overwhelmed with the love in this room.” she joked, attempting to lighten the mood.

“As a right-wing hate-monger, it is fantastic to be at a big Hollywood shindig with all these glittering celebrities that isn’t a fundraiser for Obama.”

Earlier in the evening, Coulter told Fox411 she has never seen a celebrity roast and only agreed to appear on the program to promote her book.

“There is nothing you can tell me to discourage me,” she insisted. “My whole career has been an Ann Coulter roast.”

“The Comedy Central Roast of Rob Lowe” airs Monday, Sept. 5 on Comedy Central.