Updated

Amnesty International called on the U.S. to investigate reports of civilians killed and wounded by CIA drone strikes in Pakistan in a report released Tuesday that provided new details about the alleged victims of the attacks, including a 68-year-old grandmother hit while farming with her grandchildren.

Mamana Bibi's grandchildren told the London-based rights group that she was killed by missile fire on Oct. 24, 2012, as she was collecting vegetables in a family field in the North Waziristan tribal area, a major militant sanctuary near the Afghan border. Three of Bibi's grandchildren were wounded in the strike, as were several others who were nearby, the victims said.

The U.S. considers its drone program to be a key weapon against insurgent groups that it says stages cross-border forays into neighboring Afghanistan. But the belief, widespread in Pakistan, that the strikes kill large numbers of civilians sparks resentment and complicates the two countries' ability to coordinate efforts against militants based in the country, including al-Qaida.

An even deadlier incident noted by the report — titled "'Will I be next?' U.S. drone strikes in Pakistan" — occurred in North Waziristan on July 6, 2012. Witnesses said a volley of missiles hit a tent where a group of men had gathered for an evening meal after work, and then a second struck those who came to help the wounded, one of a number of attacks that have hit rescuers, the rights group said.

Witnesses and relatives said that total of 18 male laborers with no links to militant groups died, according to Amnesty. Pakistani intelligence officials at the time identified the dead as suspected militants.

The U.S. did not respond to request for comment on the strike. President Barack Obama said during a speech in May that the U.S. does not conduct a drone strike unless there is "near-certainty that no civilians will be killed or injured." But Amnesty said the U.S. is so secretive about the program that there is no way to tell what steps it takes to prevent civilian casualties. They say it has "failed to commit to conduct investigations" into alleged deaths that have already occurred.

Several different organizations have tried to track the number of civilian casualties from nearly ten years of drone strikes in Pakistan, including the Long War Journal website, the New America Foundation think tank and the Bureau of Investigative journalism. These groups indicated that the attacks have killed between 2,065 and 3,613 people, the report said. Between 153 and 926 were thought to be civilians.

Amnesty said it is concerned that the attacks outlined in the report and others may have resulted in unlawful killings that constitute extrajudicial executions or war crimes, even though the U.S. insists the strikes are legal.

"We cannot find any justification for these killings. There are genuine threats to the USA and its allies in the region, and drone strikes may be lawful in some circumstances," said Mustafa Qadri, Amnesty International's Pakistan researcher. "But it is hard to believe that a group of laborers, or an elderly woman surrounded by her grandchildren, were endangering anyone at all, let alone posing an imminent threat to the United States."

Amnesty called on the U.S. to comply with its obligations under international law by investigating the killings documented in the report and providing victims with "full reparation."

The U.S. carried out its first drone strike in Pakistan in 2004 and has carried out nearly 350 more since then, the majority of which have been in North Waziristan. President Barack Obama significantly ramped up attacks when he took office in 2009, and the number peaked the following year with over 100 strikes. The frequency has steadily dropped since then, partly because of growing tension between Pakistan and the U.S. There have only been around two dozen strikes so far this year.

Pakistani officials regularly denounce the attacks in public as a violation of the country's sovereignty, but senior members of the government and the military are known to have supported the strikes in the past.

"Amnesty International is also extremely concerned about the failure of the Pakistani authorities to protect and enforce the rights of victims of drone strikes," said the report. "Pakistan has a duty to independently and impartially investigate all drone strikes in the country and ensure access to justice and reparation for victims of violations."

Amnesty said victims they interviewed with no apparent connection to militant groups have either received no compensation or inadequate assistance from the Pakistani government.

The top political official in North Waziristan gave Bibi's family around $100 to cover medical expenses for the children injured in the strike, even though the total cost to the family, including loss of livestock and repairs to their home, was around $9,500, the rights group said. None of the victims in the attack on the laborers received compensation, Amnesty said.

The U.S. drone policy sets a dangerous precedent "that other states may seek to exploit to avoid responsibility for their own unlawful killings," said Amnesty.

"The USA and Pakistan both have obligations under international law to investigate these and any other cases where unlawful killings might have occurred, and deliver justice," said the report. "But the USA's persistent refusal to acknowledge these strikes, coupled with Pakistan's ambiguous attitude towards the drone program and limited governance in the Tribal Areas, make it almost impossible for victims to secure the redress they need."