After 18 days, the demands of tens of thousands of anti-government demonstrators were met as Egyptian Vice President Omar Suleiman announces that Mubarak has stepped down and handed over power to the military. Nearly 300 people have been killed since anti-government protests started up in Egypt three weeks ago.
DEVELOPING: Five people were killed in the Egyptian city of Suez on Friday during anti-government protests, Al Jazeera reported.
Read earlier report below:
Egypt's military deployed on the streets of Cairo to enforce a nationwide nighttime curfew as the sun set Friday on a day of rioting and violent chaos that was a major escalation in the challenge to authoritarian President Hosni Mubarak's 30-year rule.
Still thousands in the capital Cairo defied a nationwide night curfew and were trying to storm two major government buildings -- the state TV and the Foreign Ministry. Others were praying on the streets after nightfall.
Egypt's national carrier says it has suspended its flights from Cairo for 12 hours.
The company said its flights from abroad will be able to land, but departures were canceled from 9 p.m.
Separately, a Cairo Airport official said a number of international airlines had canceled flights to the capital, at least overnight. The official was not authorized to speak to the media and spoke on condition of anonymity.
Flames rose up across a number of cities from burning tires and police cars. Even the ruling party headquarters in Cairo was ablaze in the outpouring of rage, bitterness and utter frustration with a regime seen as corrupt, heavy-handed and neglectful of grinding poverty that afflicts nearly half of the 80 million Egyptians. Hundreds were looting television sets and electric fans from the burning complex of buildings used by the ruling party.
One protester was killed in demonstrations that stretched across nearly half the provinces in Egypt, bringing the death toll for four days of protests to eight.
"I can't believe our own police, our own government would keep beating up on us like this," said Cairo protester Ahmad Salah, 26. "I've been here for hours and gassed and keep going forward, and they keep gassing us, and I will keep going forward. This is a cowardly government and it has to fall. We're going to make sure of it."
Internet and cell phone services, at least in Cairo, appeared to be largely cut off since overnight in the most extreme measure so far to try to hamper protesters form organizing. However, that did not prevent tens of thousands from flooding the streets, emboldened by the recent uprising in Tunisia -- another North African Arab nation.
There are reports Syria has also suspended internet access in response to the unrest in Egypt.
Even Nobel Peace laureate Mohamed ElBaradei, one of the country's leading pro-democracy advocates, was under house arrest after joining the protests.
"It's time for this government to change," said Amal Ahmed, a 22-year-old protester. "I want a better future for me and my family when I get married."
The sustained and intensifying demonstrations raised serious questions about whether Mubarak can keep his grip on power. Egypt is Washington's closest Arab ally, but Mubarak may be losing U.S. support. The Obama administration has publicly counseled him to introduce reforms and refrain from using violence against the protesters.
President Barack Obama convened his national security team on the growing protests in Egypt as aides voice concern about violent clashes between demonstrators and police.
Secretary of State Hillary Clinton said Friday that the United States is "deeply concerned" about the Egyptian government's violent use of force to quell protests in Cairo and elsewhere, urging both sides to show restraint.
"We are deeply concerned about the use of violence by Egyptian police and security forces against protesters," Clinton said. "The Egyptian government needs to understand that violence will not make these grievances go away."
In one of many astonishing scenes Friday, thousands of anti-government protesters wielding rocks, glass and sticks chased hundreds of riot police away from the main square in downtown Cairo and several of the policemen stripped off their uniforms and badges and joined the demonstrators.
An Associated Press reporter saw the protesters cheering the police who joined them and hoisting them on their shoulders in one of the many dramatic and chaotic scenes across Egypt on Friday.
After chasing the police, thousands of protesters were able to flood into the huge Tahrir Square downtown after being kept out most of the day by a very heavy police presence. Few police could be seen around the square after the confrontation.
The unrest began when tens of thousands poured into the streets after noon prayers in the mosques, stoning and confronting police who fired back with rubber bullets and tear gas.
Groups of thousands of protesters, some chanting "out, out, out," defied a ban that has been in place for days on any gatherings and turned out at different venues across Cairo, a city of about 18 million people. Some marched toward major squares and across scenic Nile bridges.
As the sun set, burning tires, buildings and cars sent up plumes of black smoke across the cityscape. Security officials said there were protests in at least 11 of the country's 28 provinces.
The protesters were energized by the return of ElBaradei on Thursday night after a month abroad. He declared he was prepared to lead the opposition to a regime change.
When he joined protesters after noon prayers, police fired water cannons at him and his supporters. They used batons to beat some of ElBaradei's supporters, who surrounded him to protect him.
A soaking wet ElBaradei was trapped inside a mosque while hundreds of riot police laid siege to it, firing tear gas in the streets around so no one could leave. Tear gas canisters set several cars ablaze outside the mosque and several people fainted and suffered burns.
When he returned home, police stationed outside told him he was not allowed to leave again.
Abeer Ahmed, a 31-year-old woman who showed up for ElBaradei with her toddler, said she has a law degree but makes a living cleaning homes.
"Nothing good is left in the country," she said. "Oppression is growing."
Some of the most serious violence Friday was in Suez, where protesters seized weapons stored in a police station and asked the policemen inside to leave the building before they burned it down. They also set ablaze about 20 police trucks parked nearby. Demonstrators exchanged fire with policemen trying to stop them from storming another police station and one protester was killed in the gun battle.
In the upscale Mohandiseen neighborhood, at least 10,000 were marching toward the city center chanting "down, down with Mubarak." The crowd later swelled to about 20,000 as they made their way through residential areas.
Residents looking on from apartment block windows waved and whistled in support. Some waved the red, white and black Egyptian flags. The marchers were halted as they tried to cross a bridge over the Nile, when police fired dozens of tear gas canisters.
In downtown Cairo, people on balconies tossed cans of Pepsi and bottles of water to protesters on the streets below to douse their eyes, as well as onions and lemons to sniff, to cut the sting of the tear gas.
At Ramsis square in the heart of the city, thousands clashed with police as they left the al-Nur mosque after prayers. Police used tear gas and rubber bullets and some of the tear gas was fired inside the mosque where women were taking refuge. Hundreds later broke through police cordons to head to the main downtown square, Tahrir. But they were stopped by police firing tear gas.
Near Tahrir, hundreds of riot police in a cluster moved in, anticipating the arrival of large crowds. A short while later, thousands of protesters marched across a bridge over the Nile and moved toward the square, where police began firing tear gas at them.
Hundreds of protesters played a cat-and-mouse game with riot police in a square just behind the famed Egyptian Museum on Tahrir Square. Police were using tear gas and the protesters responded with rocks and chants of "illegitimate, illegitimate," a reference to Mubarak's regime.
Later, television footage showed a chaotic and violent scene where protesters were throwing rocks down on police from a highway overpass near Tahrir Square, while a police vehicle sped through the crowd spraying tear gas on demonstrators.
Clusters of riot police with helmets and shields were stationed around the city, at the entrances to bridges across the Nile and other key intersections.
The troubles were preventing trains from coming to Cairo, said security officials.
In Assiut in southern Egypt, several thousand demonstrators clashed with police that set upon them with batons and sticks, chasing them through side streets.
Mubarak has not been seen publicly or heard from since the protests began Tuesday. While he may still have a chance to ride out this latest challenge, his choices are limited, and all are likely to lead to a loosening of his grip on power.
A Facebook page run by protesters listed their demands. They want Mubarak to declare that neither he nor his son will stand for next presidential elections; dissolve the parliament holds new elections; end to emergency laws giving police extensive powers of arrest and detention; release all prisoners including protesters and those who have been in jail for years without charge or trial; and immediately fire the interior minister.
Mubarak has not said yet whether he will stand for another six-year term as president in elections this year. He has never appointed a deputy and is thought to be grooming his son Gamal to succeed him despite popular opposition. According to leaked U.S. memos, hereditary succession also does not meet with the approval of the powerful military.
Mubarak and his government have shown no hint of concessions to the protesters who want political reform and a solution to rampant poverty, unemployment and rising food prices.
Continuing the heavy-handed methods used by the security forces the past three days would probably buy the Mubarak regime a little time but could strengthen the resolve of the protesters and win them popular sympathy.
The alternative is to introduce a package of political and economic reforms that would end his party's monopoly on power and ensure that the economic liberalization policies engineered by his son and heir apparent Gamal over the past decade benefit the country's poor majority.
He could also lift the emergency laws in force since 1981, loosen restrictions on the formation of political parties and publicly state whether he will stand for another six-year term in elections this year.
Friday's demonstrations also got a boost from the endorsement of the country's biggest opposition group, the Islamic fundamentalist Muslim Brotherhood. The group called its supporters to join the protests on Friday.
The Brotherhood, outlawed since 1954, is Egypt's largest and best organized opposition group. It seeks to establish an Islamic state. It renounced violence in the 1970s and has since been a peaceful movement. Its network of social and medical services has traditionally won it popular support, but its detractors say its involvement in politics has chipped away at its support base.
It made a surprisingly strong showing in 2005 parliamentary elections, winning 20 percent of the legislature's seats, but it failed to win a single seat in the latest election late last year. The vote is widely thought to have been marred, rigged to ensure that Mubarak's ruling party win all but a small fraction of the chamber's 518 seats.
Egypt's four primary Internet providers -- Link Egypt, Vodafone/Raya, Telecom Egypt, Etisalat Misr -- all stopped moving data in and out of the country at 12:34 a.m., according to a network security firm monitoring the traffic. Telecom experts said Egyptian authorities could have engineered the unprecedented cutoff with a simple change to the instructions for the companies' networking equipment.
The Internet appeared to remain cut off in Cairo but was restored in some smaller cities Friday morning. Cell-phone text and Blackberry Messenger services were all cut or operating sporadically in what appeared to be a move by authorities to disrupt the organization of demonstrations.
Authorities appear to have been disrupting social networking sites, used as an organizing tool by protesters, throughout the week. Facebook, Twitter and Blackberry Messenger have all seen interruptions.
The Associated Press contributed to this report.