Updated

A New York man whose two previous convictions for killing his estranged wife were reversed by appeals courts is set to go on trial again.

Jury selection for the latest murder trial of 55-year-old businessman Calvin Harris began Thursday and is expected to last into next week.

Harris is accused of killing his estranged wife, Michele, on Sept. 11, 2001, at their home in the town of Spencer, northwest of Binghamton. Prosecutors say the 35-year-old woman was killed while their four young children were asleep upstairs. Her body has never been found, and authorities have not found a murder weapon.

The state's top court ordered a new trial for Harris in 2012 after faulting the judge's handling of hearsay testimony and a prospective juror who acknowledged having a pre-existing opinion.