MINNEAPOLIS (AP) Tyler Duffey took a no-hit bid into the sixth inning of his second big league game and pitched the Minnesota Twins over the Cleveland Indians 4-1 Saturday night.

Duffey, roughed up by Toronto earlier this month in his debut, came back to earn his first victory in the majors. A one-out double by Francisco Lindor in the sixth was the only hit Duffey (1-1) permitted before leaving at the end of the inning.

The 24-year-old righty struck out seven and worked around five walks. Relievers Casey Fien, Kevin Jepsen and Glen Perkins each pitched an inning in the combined four-hitter.

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Eddie Rosario and Chris Herrmann hit back-to-back homers in the fifth off Josh Tomlin (0-1), who made his first major league start since shoulder surgery in April.

Brian Dozier added a late two-run homer for Minnesota, which had lost three straight to the Indians.

Tomlin lasted 6 1-3 innings. He scattered two hits over the first four innings before leaving a high fastball over the plate for Rosario leading off the fifth.

After Rosario launched the pitch 401 feet into the right field seats, Herrmann followed with his second homer of the season to the same place.

That was more than enough room for Duffey, who clearly recovered from a rough start 10 days earlier at Toronto. He allowed six runs, five hits, two walks in that outing, and threw 60 pitches in just two innings.

Dozier hit his 25th homer, a two-run drive in the eighth off Bryan Shaw.

Roberto Perez drove in Cleveland's run with long, two-out single in the ninth off Perkins.

TRAINER'S ROOM

Indians: Manager Terry Francona said OF Michael Brantley received treatment for his sore left throwing shoulder, and doubted he would play Sunday. ''I think the best thing that we could maybe hope for is he swings the bat tomorrow. I don't want him to just go cold turkey into a game.'' . 2B Jason Kipnis (shoulder) is eligible to come off the DL on Monday, although Francona said he didn't know if he would be activated immediately. . Francona said RHP Cody Anderson (left oblique strain) would meet the team in Boston and likely throw a bullpen session on Monday.

UP NEXT

The Indians will start RHP Carlos Carrasco (11-8) on Sunday, four days after allowing just two runs in eight innings against the Yankees. Carrasco has thrown eight or more innings while allowing four or fewer hits in three straight starts. LHP Tommy Milone (5-3) is set to come off the DL for the Twins after being out with a strained elbow. Milone will make his first start since July 31, when he allowed four runs on 11 hits in six innings against Seattle.