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It’s the ultimate bust-out role.

Portraying tragic bombshell Anna Nicole Smith in the Lifetime biopic “Anna Nicole,” airing June 29, actress Agnes Bruckner goes from a B-cup to a DD — with absolutely no surgery involved.

Her secret? State-of-the-art prosthetics designed by three-time Academy Award winner Greg Cannom (“Mrs. Doubtfire,” “The Curious Case of Benjamin Button”) and painstakingly applied by experienced makeup artists Todd McIntosh and David De Leon.

“David and I would apply the breasts in tandem,” McIntosh told The Post of the miracle falsies, made of gel-filled silicone and designed to be applied individually.

“This created the freedom for them to move and jiggle more like flesh,” he explained. “It would have been impossible for her to do the pole dancing or fill out some of the outfits without this innovation.”

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And fill them out she does. As Anna Nicole, Bruckner gyrates at a strip club, preens and poses for Playboy, dances wildly on a table in the skimpiest of dresses and even dives into a pool. Yet the faux DDs never give themselves away.

For Bruckner, who has described herself as “flat-chested,” wearing the prosthetics was certainly an uplifting — but bizarre — experience.

“They couldn’t have been any more real looking,” she said. “It was so strange, wearing them for the first time. I was standing there ‘topless,’ but it was really like I had a shirt on because there was nothing exposed of my own. I’d look at myself, and I kept thinking, ‘Oh, my God, could you imagine if they really were that big?’ ”

Go to The Post for more.