A large Wetzel & Sons moving truck was spotted leaving their home Thursday afternoon but the company refused to comment.
"We don't give out any information on our clients," a spokesperson told the gossip magazine.
Reports have been flying since late September that the Hollywood power couple was splitting due to Kutcher's alleged one-night-stand with 22-year-old, Sara Leal, on the day of Kutcher's sixth wedding anniversary with Moore.
Leal, an administrative assistant originally from Texas, described in detail a naked hot tub huddle she shared with Kutcher that later led to a hook-up with the "Two and a Half Men" star in the early hours of September 24.
Both Moore, 48, and Kutcher, 33, have refused to comment on the alleged incident.
But last weekend they were spotted camping together in the outdoors of Southern California, with their Kabbalah instructor on hand, to observe the Jewish day of atonement, Yom Kippur.