Ladies in Red: Hollywood Stars Work the Carpet at the Heart Truth's Red Dress Fashion Show

To officially kick off Fashion Week in New York City, the Heart Truth’s Red Dress Fashion show brings together some of Hollywood’s biggest stars to work the runway to raise awareness for heart disease.

Wearing stunning red gowns designed by the industry’s biggest names, stars like Denise Richards, Audrina Patridge, Patti LaBelle and Suzanne Somers all walked the catwalk in designs by Matthew Williamson, Badgley Mischka, Zang Toi and Ina Soltani.

The Heart Truth outs on the fashion show twice a year to raise awareness for women about heart disease. The Red Dress was introduced as a national symbol for women and heart disease awareness in 2002 by the National Heart, Lung and Blood Institute.

Singer Patti LaBelle told FOX411 that she suffers from a baby heart murmur, and walked to remind women to “remind themselves to get checked up,” as heart disease is the number one killer of women.

Surgeon General Regina Benjamin revealed that the event was her first real fashion show, but noted that, fun aside, the event’s main priority was prevention.

“We really want to prevent heart attacks and particularly in women, we want to raise awareness that you know what to look for if you have any signs or symptoms and when to call for help. And to have these celebrities here to help us get that message out is so important,” she said.

Actress and fitness/lifestyle author Suzanne Somers spoke of a similar message, urging women to “pay attention to your genetics but also to your diet and lifestyle because every choice you make today will affect your outcome.”