Comedian George Lopez's wife, Ann Serrano Lopez has filed for divorce after 17 years of marriage and giving her husband one of her kidneys.
Serrano Lopez filed her petition, citing irreconcilable difference, on Tuesday in Los Angeles.
The pair announced their breakup in September and said they would remain partners in a charitable foundation.
For now, Serrano Lopez is seeking physical custody of their 14-year-old daughter Ann Lopez.
The filings do not offer any additional details or separation date about the couple’s split, who married in September 1993.
The 49-year-old comedian hosts the talk show "Lopez Tonight" on TBS.
The Associated Press contributed to this report.