Nancy Guthrie search: Donna Rotunno reacts to DNA testing update in missing grandmother case

Criminal defense attorney Donna Rotunno reacts to updates in the search for missing Arizona grandmother Nancy Guthrie. Rotunno explains the challenges investigators face after crime scene hair samples failed to yield a DNA profile.

Defense attorney Donna Rotunno discusses the search for Nancy Guthrie, an Arizona grandmother who disappeared in February 2026. Investigators announce that DNA could not be profiled from hair recovered at the crime scene, creating a major setback. Rotunno analyzes the scientific limitations of forensic testing and what steps Pima County Sheriff Chris Nanos might take next to locate her.