This whole Obama thing does remind me of a basic truism in life, really.

Never underestimate the power of a slight.

I know a very, very big Republican cabinet official who refuses to grant me any interview any time because one time I had the audacity to cancel his appearance on my show after I discovered that the exclusive chat I had been promised wasn't exclusive at all. He had appeared everywhere and seemingly with everyone else earlier.

I knew a CEO who so bristled at my line of questioning that he personally called my boss to get me fired. Actually, several guests have done that.

A top senator so insulted by my badgering over how he arrived at numbers for his program that he just refused to do my program ever again. His name rhymes with Schumer.

Sometimes I'm surprised by this stuff. But mostly, I am not.

I've discovered, the bigger the ego, usually the bigger offense to the slight. And the bigger the revenge.

I guess it's human nature. I can't tell you the people who go after me. And yea, a lot of times it doesn't thrill me.

But it's the business. It's life. I go on. Even when the attacks turn personal. Even when some go so far as to call me fat. Can you imagine???!!

But I'm always, always ready for that one.

And here's what I say: It's true, the camera really does add 50 pounds.

And then, I get some dinner.

Watch Neil Cavuto weekdays at 4 p.m. ET on "Your World with Cavuto" and send your comments to cavuto@foxnews.com

Neil Cavuto serves as senior vice president, anchor and managing editor for both FOX News Channel (FNC) and FOX Business Network (FBN). He is anchor of FNC's Your World with Cavuto - the number one rated cable news program for the 4 p.m. timeslot - as well as the FNC Saturday show Cavuto on Business. He also hosts Cavuto on FBN weeknights at 8 p.m. In addition to anchoring daily programs and breaking news specials on FNC and FBN, Cavuto oversees business news content for both networks and FNC's weekend business shows, including Bulls & Bears, Forbes on Fox, and Cashin' In. Click here for more on Neil Cavuto.