Updated

JACKSONVILLE, Fla. (AP) -- Jacksonville Jaguars running back Leonard Fournette could miss his first game of the season because of a sprained right ankle.

The Jaguars list Fournette as questionable to play Sunday at Indianapolis. He did not practice all week. Fournette ranks second in the NFL in rushing with 596 yards and is tied for the league lead with seven touchdowns.

Receiver Marqise Lee (knee) and safety Tashaun Gipson (neck) also were listed as questionable on Friday's injury report. Lee and Gipson practiced on a limited basis Friday.

Center Brandon Linder (illness) was ruled out for the third consecutive game. Linder is expected to return after Jacksonville's bye next week.

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