HOUSTON (AP) Indianapolis quarterback Andrew Luck was inactive on Thursday night against the Houston Texans because of a right shoulder injury.

It will be the second straight game Luck has sat out after not missing a game in his career before last week.

Matt Hasselbeck will start in his place in a matchup of AFC South foes. The 40-year-old Hasselbeck threw for 282 yards with one touchdown in a 16-13 overtime win over the Jaguars on Sunday. Josh Johnson will be Hasselbeck's backup.

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Inactive for the Texans are receivers Nate Washington (hamstring) and Cecil Shorts (shoulder).

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AP NFL website: www.pro32.ap.org and http://twitter.com/AP-NFL