An interception returned for a touchdown is one of the most exciting plays in football. It's a complete momentum changer for both sides and usually has a huge impact on the outcome of a game.
In this case, it didn't lift the Buffalo Bills to victory -- not that the game counted anyway -- but it will be seen on highlight reels for the foreseeable future.
Bills cornerback Ron Brooks made one of the most ridiculous pick-sixes you'll ever see. Lions quarterback Dan Orlovsky hit Jeremy Ross on the outside for what appeared to be a completion. Only, Ross never came down with the ball cleanly as it popped out of his hands and into the hands of Brooks who was off to the races.
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That is by far the easiest pick-six Brooks, or any cornerback, will ever have. No one came close to catching him and preventing the touchdown.