Tight end Julius Thomas left Jacksonville's preseason opener against Pittsburgh with a hand injury.
Thomas injured his left hand when Steelers cornerback William Gay tackled him on a 2-yard gain in the first quarter. It came on Jacksonville's second play of the preseason and Thomas' first game with the Jaguars since signing a five-year, $46 million contract that included $24 million guaranteed.
Thomas headed to the locker room for tests, and the team said his return was questionable.
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Thomas' injury left the Jaguars without their top two draft picks and top two free-agent acquisitions. First-round defensive end Dante Fowler Jr. (knee) is out for the season. Second-round running back T.J. Yeldon (hand) and free-agent defensive end Jared Odrick (knee) missed Saturday's game but should return next week.