The latest news in the arrest of two nephews of the powerful first lady of Venezuela Cilia Flores on U.S. drug charges. All times local in Caracas.

12 a.m.

Two nephews of Venezuela's powerful first lady have been indicted on U.S. narcotics charges.

An indictment unsealed on Thursday accuses Efrain Campos and Francisco Flores of conspiring to smuggle cocaine into the United States. The defendants were expected to appear in federal court in Manhattan later in the day.

The indictment says the pair participated in meetings in Venezuela about a shipment of cocaine that was to be sent to the U.S. via Honduras. It provides no other details.

The arrest of Efrain Campos and Francisco Flores is likely to exacerbate already tense relations between the U.S. and Venezuela and cast a hard look at U.S. accusations of drug trafficking at the highest levels of President Nicolas Maduro's socialist administration.