A casino bus full of tourists overturned in northwestern Mississippi on Sunday, killing three people and injuring several others.

The bus belonged to Harrah's Tunica and was carrying 43 people when it flipped over in a median at an intersection in Tunica, Tunica County spokesman Larry Liddell said.

Tourists on the bus were headed to the airport for a flight to South Carolina, where many were from, officials said.

The bus was the only vehicle involved in the accident, which was still under investigation, Mississippi Highway Patrol Sgt. Leslie White said.

The injured passengers were taken to hospitals in Memphis, Tenn., about 35 miles to the north.

Twenty-seven people were taken to Baptist Memorial Hospital, spokesman Thomas Whitehead said. One was in critical condition and five were being held for observation. The rest had what Whitehead described as minor injuries.

Messages left at Regional Medical Center in Memphis were not immediately returned.

Harrah's Entertainment operates 50 casinos worldwide, including three in Tunica: Harrah's Tunica, Horseshoe Casino and the Sheraton Casino & Hotel. The area along the Mississippi River in the northwest corner of the state is best known for its bustling casinos.

"At this time, we're focusing on the health and welfare of the guests involved in this tragic accident," company officials said in a statement. The company set up a telephone hot line to give information and assistance to relatives of the crash victims.