The Academy Award nominated star of "The Fabulous Baker Boys" and "Dangerous Liaisons" thanked her mother and father for supporting her decision to become an actress.
"She taught me that I could do anything and that I should have a career before I get married," she said. Her father, she said, "taught me that you can make something of yourself if you work hard."
Pfeiffer is currently on the screen playing the nasty Velma Von Tussle in "Hairspray" and will soon be seen as the evil witch Laima in the fairy tale "Stardust," set for release Aug. 10.
"You are two of the nicest men on the planet," she told them.