The 31-year-old actress said she loves the medium of television and the routine it provides, but that "Housewives" will be her last series.
"I would never leave `Desperate Housewives,"' Longoria told The Associated Press. "I love doing both [TV and film], but I would never do another TV show after `Desperate Housewives.' No."
Longoria, who plays saucy Gabrielle Solis on the ABC dramedy, can next be seen on the big screen in "How I Met My Boyfriend's Dead Fiancee," due in 2007. She made her mainstream movie debut opposite Michael Douglas in "The Sentinel" earlier this year.
The third season of "Desperate Housewives" begins Sept. 24.