Watch "Hannity & Colmes" weeknights at 9 p.m. ET!

Where is Natalee Holloway (search)? As the search continues for the missing Alabama teen, friends and family wait anxiously for credible leads to her whereabouts while officials in Aruba (search) scramble to find suspects. Tonight, Aruba government spokesman Ruben Trapenberg weighs in on why finding the 18-year-old is "priority No. 1" for the Dutch Caribbean island.

Then, would Natalee ever go off with strangers? We'll ask her aunt and uncle.

And, classmate Haley Uncapther talks to Sean and Alan about her friend.

Plus, we’ll go inside the Holloway investigation with former LAPD Detective Mark Fuhrman. He’ll break down the leads in Natalee’s disturbing disappearance as cops continue to search for her whereabouts.

Then, why has Fresno Mayor Alan Autry issued a call to close the Mexican border? We’ll ask Mayor Autry himself tonight.

Plus, we're live in Santa Maria as the world awaits a verdict in the Michael Jackson (search) trial.

This and much more ... Don't miss your opportunity to join the debate tonight at 9 p.m. ET!

Real journalism: fair and balanced. That's why we're No. 1 — FOX News Channel.

About the Show

Fast-paced and hard-hitting, "Hannity & Colmes" brings viewers a heated discussion in a nightly face-off. Relishing in controversial topics, personalities and social issues, conservative radio commentator Sean Hannity and liberal radio personality Alan Colmes offer their points-of-view in an often animated, always compelling debate.

But, unlike similar debate shows — which often appear scripted — "Hannity & Colmes" conducts a live, spur of the moment deliberation on politics and social topics. Also, differentiating the show is its dedication to "move away from the Beltway," bringing audiences an alternative discussion program without the "in" comments.

Adding fuel to the fire, several high-profile guests have joined the program on a wide-range of topics.

"With guests who are 'in the middle of the fight,' we're able to hear their point-of-view on the topics, as well as advance our own feelings," said Hannity.

"Believe it or not, I agree with that statement," quipped Colmes.