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First, Vioxx. Now, Celebrex? Pfizer (search) announces it has found an increased risk of heart problems with patients taking its painkiller.

Pfizer CEO Hank McKinnell (search) explains his company's response to Celebrex findings.

How will this bombshell impact the industry's future and your portfolio? We'll get a read from Dr. Bob Froehlich, chief investment strategist at Deutsche Asset Management; Wendell Perkins, chief investment officer of the Johnson Family of Funds; Price Headley, founder of BigTrends.com, and Tobin Smith, chairman of ChangeWave Research.

What's left for patients to use as an alternative? We'll get insight from Dr. Isadore Rosenfeld, FOX News medical consultant.

And, we'll ask Forbes' managing editor Dennis Kneale why he thinks Pfizer is botching their handling of the Celebrex findings ... big-time.

Santa Claus (search) himself drops by the studio to reveal whether Neil has been naughty or nice this year.

And, we'll find out how Santa delivers so many packages each year from Doug Duncan, CEO of FedEx Freight.

About the Show

"Your World with Neil Cavuto" offers news and insight on Wall Street and other market activities, while wrapping up the business news of the day. Named "the best interviewer in broadcast business news" by The Journalist and Financial Reporter, Neil Cavuto identifies why and how events happen.

"We bring the most influential players in the business world to our viewers, offering insights on the day's news and the market's broader trends," said Cavuto. "This is business news that matters — information we need to know to make the right choices."

More than just facts and figures, "Your World with Cavuto" gets to the heart of the matter with in-depth reporting from Dagen McDowell, FOX Business correspondent, and analysis from our FOX Business News All-Stars:

Terry Keenan, host of Cashin' In
Brenda Buttner, host of Bulls & Bears
David Asman, host of Forbes on Fox
Stuart Varney, FOX Business News contributor