Steve Centanni reports: Saddam’s sons Uday (search) and Qusay (search) were killed when U.S. soldiers stormed a house in the northern Iraqi city of Mosul. FOX News correspondent Steve Centanni was the first on the scene, he will update the situation.

Guest Preview: What will be the significance at home and abroad now that it is confirmed that Saddam’s sons were taken out in Iraq? Retired Maj. Gen. Robert Scales will discuss the situation.

Plus:

Bret Baier reports: With two of Saddam's closest links dead, are we closer to finding Saddam? We'll investigate.

Jim Angle reports: What will be the reaction in the Capital? Will there be a unanimous response or will partisan politics be the result? We’ll follow the situation.

Jennifer Eccleston reports: Bloodshed has become too common in Liberia (search) as more than 600 civilians have been killed in the capital Monrovia (search) as a result of the rebel fighting in the past few days. Is there a peaceful solution to this tragic situation? What involvement should U.S. troops have in the matter? We’ll assess the situation.

Rebecca Gomez reports: West Virginia welcomes home a POW hero of Operation Iraqi Freedom, Pfc. Jessica Lynch (search). Lynch offered thanks to her doctors and well-wishers at a special homecoming demonstration. We’ll have the highlights from the celebration.

Carl Cameron reports: Sen. John Edwards (search), D-N.C., kick starts his campaign with the opening of his headquarters in South Carolina. The presidential hopeful has raised more money from South Carolina donors during the past three months than all of his opponents combined. How does this affect the race for the Democratic nomination? We’ll get the details.

Brian Wilson reports: Is partisan bickering getting out of control on the Hill? Why is House Minority Leader Nancy Pelosi (search) threatening that it is going to be a week from hell for Republicans? Don’t miss this story.

Details on those stories and more on Special Report with Brit Hume.

— Guests and topics are subject to change