Guests and Topics for May 21

First lady Laura Bush joins us live from Prague, to explain her role as the official representative in a mission to highlight US-led efforts to rebuild Afghanistan.

Why did the nation's intelligence community fail to predict and prevent the attacks of September 11? We'll ask one of the men leading the investigation into the breakdown, Sen. Chuck Grassley, R-Iowa.

How long was the FBI aware that Usama bin Laden and his terrorist network were training pilots in the United States and elsewhere around the world? Jack Devine, president of the Arkin Group, weighs in.

Does this weekend's spate of suicide bombings in Israel suggest a lack of control by Yasser Arafat? We'll ask Rob Sobhani, professor of Mideast Relations at Georgetown University.

Was the assassination of Ahmed Shah Masoud, head of Afghanistan's Northern Alliance, part of Usama bin Laden's preparations for September 11? Josh Meyer, staff writer for the Los Angeles Times, reveals bin Laden's larger plan.

Plus, we'll be joined by Hall of Fame quarterback Joe Namath, as he kicks off the 'Arthritis Huddle' — a new initiative to provide doctors and osteoarthritis patients the resources to tackle disabling disease.

And, actress Cheryl Ladd drops by the studio.

Don't miss a moment with us! Watch FOX & Friends weekdays at 6 a.m. ET and weekends at 7 a.m. ET on the Fox News Channel.

About the show...

This offbeat morning show features anchors E.D. Donahey, Steve Doocy and Brian Kilmeade. They take a look at the day's news, sports and weather from a different perspective. It is an interactive show where you can call in to voice your opinion or have your e-mail read. Anything can happen and usually does!

Every day, syndicated radio host and FOX contributor Mancow joins the show with unique insights and commentary on the day's news events, bringing his own brand of offbeat and irreverent humor from his WKQX studio in Chicago.

Plus, now you can watch America's No. 1 cable news morning show seven days a week, as hosts Juliet Huddy, Bob Sellers and Bill McCuddy man the morning show ship on the weekends!

There's no telling what FOX & Friends will be cooking up outside our Manhattan studios on 6th Avenue. So, if you are in New York, drop by - the Morning Crew loves an audience! We are located at:  1211 Avenue of the Americas, between 47th and 48th streets.

- Note: Guests and topics subject to change.