SAN DIEGO (AP) Clayton Kershaw was brilliant on opening day, holding San Diego to one hit in seven innings and striking out nine to lead rookie manager Dave Roberts and the Los Angeles Dodgers to a record-setting 15-0 victory against the Padres on Monday.

It was the most lopsided opening day shutout in major league history. The previous mark was a 14-0 win by the Pittsburgh Pirates over the Cincinnati Reds in 1911, according to STATS.

Kershaw (1-0) allowed Jon Jay's single with two outs in the third and then retired his last 13 batters. The lefty improved to 4-0 in six opening day starts.

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Adrian Gonzalez had three of Los Angeles' 17 hits and three RBIs, and A.J. Ellis also drove in three runs. Chase Utley had three hits and two RBIs.

Roberts, who played for both the Dodgers and Padres, and San Diego first-year manager Andy Green exchanged lineup cards before the game. It was the first opening day meeting of two rookie skippers since Fredi Gonzalez of Florida and Manny Acta of Washington in 2007.

It was the worst opening day loss in the Padres' 48-year history. San Diego had only four hits.

Five straight Dodgers reached against Tyson Ross (0-1) in the five-run sixth.

NATIONALS 4, BRAVES 3, 10 INNINGS

ATLANTA (AP) - Daniel Murphy was a huge hit in his Washington debut with a home run and a go-ahead double in the 10th inning, and the Nationals rallied past Atlanta in their season opener.

NL MVP Bryce Harper homered in his first plate appearance of the season, and the Nationals made a winner of Dusty Baker in his first game as their manager.

Washington tied it in the ninth on Michael Taylor's sacrifice fly to shallow center field. Atlanta nearly escaped with a game-ending double play, but Jayson Werth scored when catcher A.J. Pierzynski dropped Ender Inciarte's accurate throw that beat Werth to the plate.

Murphy's one-out double off Eric O'Flaherty (0-1) drove in Ryan Zimmerman from second base. Zimmerman reached on a two-base throwing error by second baseman Gordon Beckham.

Blake Treinen (1-0) pitched a scoreless ninth and Jonathan Papelbon got three straight outs for the save.

Freddie Freeman and Adonis Garcia homered against Nationals ace Max Scherzer, who gave up two runs and three hits in seven innings.

GIANTS 12, BREWERS 3

MILWAUKEE (AP) - Denard Span homered and drove in five runs in his San Francisco debut, and the Giants beat Milwaukee in their opener despite a sluggish start from under-the-weather ace Madison Bumgarner.

Span hit a three-run shot in the eighth inning and Joe Panik and Buster Posey followed with home runs off Ariel Pena.

It marked the first time the Giants had connected for three straight homers on opening day. It was the first time any team had done it in an opener since the Padres in 1997, the Giants said in citing the Elias Sports Bureau.

Matt Duffy helped out with a home run and four RBIs. Brandon Belt doubled twice and singled for San Francisco.

The Giants scored quickly against Wily Peralta (0-1) and bailed out the ailing Bumgarner (1-0), who left after the fifth with a four-run lead. The 2014 World Series MVP allowed five hits, five walks and three runs.

RANGERS 3, MARINERS 2

ARLINGTON, Texas (AP) - Cole Hamels handed Seattle ace Felix Hernandez his first opening day loss, and Texas managed to win with just one hit.

Prince Fielder blooped an RBI single off Hernandez during a three-run fifth inning that included three walks and two errors.

Seattle had a chance to join the Boston Beaneaters (1887-96) as the only major league clubs to win 10 straight openers. Robinson Cano and Kyle Seager homered early for the Mariners, but the midgame mistakes cost them the lead in the debut of manager Scott Servais.

Hernandez (0-1) fell to 6-1 in nine opening day starts.

Hamels (1-0) struck out eight in seven innings of four-hit ball. Shawn Tolleson worked a perfect ninth for the save.

ORIOLES 3, TWINS 2

BALTIMORE (AP) - Matt Wieters singled home the winning run with two outs in the ninth inning, and Baltimore withstood two long rain delays in a season-opening victory over Minnesota.

A game that was scheduled to start at 3:05 p.m. finally ended at 8:44, even though the playing time was only 2 hours, 48 minutes.

With the score tied at 2, Chris Davis drew a two-out walk from Kevin Jepsen (0-1). After newcomer Mark Trumbo followed with his fourth single, Wieters lined a single up the middle.

Zach Britton (1-0), the sixth Orioles pitcher, worked a perfect ninth. Baltimore has won 13 of its last 16 openers, including six straight.

Minnesota hasn't won on opening day since 2008.

REDS 6, PHILLIES 2

CINCINNATI (AP) - Zack Cozart had three hits and drove in the tying run with a sacrifice fly in the eighth inning, and Joey Votto followed with a bases-loaded single that sent Cincinnati over Philadelphia in an opener matching the majors' two worst teams from last season.

The Reds scored five times in the eighth against Philadelphia's work-in-progress bullpen. Jay Bruce completed the rally with a two-run single in front of 43,683 fans, the largest regular-season crowd in Great American Ball Park history.

Votto struck out in his first three at-bats but singled off left-hander James Russell for a 4-2 lead.

Ross Ohlendorf (1-0) got the win by striking out the only batter he faced. David Hernandez (0-1) took the loss.

Freddy Galvis hit a two-run homer for the Phillies, and Jeremy Hellickson allowed three hits - all by Cozart - in six innings.

BLUE JAYS 5, RAYS 3

ST. PETERSBURG, Fla. (AP) - Josh Donaldson, Michael Saunders and Josh Thole homered to help R.A. Dickey and Toronto beat Tampa Bay.

All three home runs were hit off Drew Smyly (0-1), with Donaldson connecting for a solo shot in the fifth inning, Saunders delivering a two-run homer in the fourth and Thole going deep on a third-inning drive that umpires initially ruled was a double after a fan interfered by catching the ball before it reached the stands.

The call was reversed after a replay review, erasing a 1-0 Tampa Bay lead.

Dickey (1-0) gave up three runs in five-plus innings. Roberto Osuna worked a perfect ninth for his second save.