Dustin Brown's first match since beating Rafael Nadal ended in defeat.
The German qualifier followed up his surprising win over the two-time Wimbledon champion with a 6-4, 7-6 (3), 4-6, 6-3 loss to 22nd-seeded Viktor Troicki of Serbia on Saturday in the third round.
Brown was again playing his serve-and-volley game on Court 3 against Troicki, but it didn't work as well as it did against Nadal on Thursday.
Brown, whose father is Jamaican and mother is German, reached the third round at the All England Club for the second time in his career, but he has never been any further. He also made it that far in 2013.
It was this year that he made a name for himself in the tennis world, however.
Although Nadal has been struggling this season and was eliminated from the French Open in the quarterfinals for only his second loss ever at Roland Garros, he was still expected to get past the 30-year-old Brown at Wimbledon. But Brown's play at the net troubled Nadal throughout their match, and sent the Spaniard home early for the fourth year in a row.
Beating Nadal at Wimbledon doesn't necessarily lead to greatness, however. All four players that beat Nadal have failed to win their next match.
Also on Day 6 at Wimbledon, Roger Federer was first up on Centre Court facing Sam Groth of Australia. Federer has won the Wimbledon title seven times, and one more would give him the record for most men's singles titles at the grass-court Grand Slam tournament.
Andy Murray, the 2013 champion, was also scheduled to play on Centre Court later Saturday. The British player will face Andreas Seppi of Italy.
On Court 1, Wimbledon's marathon man will be at it again. John Isner, who won the longest tennis match in history in 2010, will resume his match against Marin Cilic with the scores even at 10-10 in the fifth set.
Isner beat Nicolas Mahut 70-68 in the fifth set in that epic match five years ago.
For the women, defending champion Petra Kvitova was to face former top-ranked player Jelena Jankovic of Serbia, also on Centre Court. Kvitova has only lost three games through two rounds and has spent a mere 92 minutes on court so far this tournament.
In early results, No. 20 Roberto Bautista-Agut of Spain advanced to the fourth round by beating Nikoloz Basilashvili of Georgia 7-6 (4), 6-0, 6-1. Also, Monica Niculescu of Romania beat Kristyna Pliskova of the Czech Republic 6-3, 7-5.