Real Madrid was drawn Friday to face crosstown rival Atletico Madrid in the quarterfinals of the Champions League in a rematch of last year's final.
Real Madrid won its record 10th title in the continental competition last year with a 4-1 victory over Atletico.
Bayern Munich, the 2013 champion, will face FC Porto while Paris Saint-Germain and Barcelona will meet again after playing in the group stage this season.
The final match-up pits Juventus against Monaco.
Atletico and Real Madrid will be facing each other for the seventh and eighth times this season, with Real Madrid yet to register a win against its local rival. Last month, Real Madrid was handed its biggest defeat in four years as it slumped to a 4-0 loss at Atletico in the Madrid derby.
The first leg will be played at Atletico's ground, either on April 14 or April 15, with the return game on April 21 or 22.
"They're (Atletico) a side who know how to compete, they let in few goals, are good from dead balls and get the best out of each situation," said former Real Madrid player Emilio Butragueno, now a director of institutional relations at the club. "You never know if it's an advantage playing the second leg at home. We have to be at our best because we know exactly the difficulties that we're going to face."
This year's final will take place at the Olympic Stadium in Berlin on June 6.
PSG will be without its main striker against Barcelona for the first leg at the Parc des Princes after Zlatan Ibrahimovic was suspended for one game following his sending off against Chelsea in the previous round.
PSG beat Barcelona 3-2 at home in the group stage but lost 3-1 at the Camp Nou. The teams also met in the quarterfinals two seasons ago, with Barcelona progressing on away goals.
The German team will be favored against the unexperienced Portuguese side, which beat Bayern in the 1987 European Cup final, after reaching the quarterfinals for the 14th time.
Porto won the 2004 trophy under coach José Mourinho by defeating Monaco in the final.
"The atmosphere in Porto is very heated," Bayern goalkeeper Manuel Neuer said. "With these fans it won't be easy for us, but we have played in many different stadiums with varying atmospheres and we will know what to expect."